Use of Equipoise can lead to excess estrogen formation in some cases and antiestrogens such as Nolvadex can be effective options to prevent or control estrogenic side effects like gynecomastia and oily skin. The use of Equipoise should not be made without medical advice and the doses should not be increased or decreased without prior medical approval. Equipoise use is not recommended to pregnant or breastfeeding women or people who have a hypersensitivity to Equipoise or any of its ingredients. Equipoise use is not recommended to people suffering from severe health complications such as prostate cancer or breast cancer.